"KRAZATI (adagrasib) is an irreversible inhibitor of KRAS G12C and belongs to the RAS GTPase family. KRAZATI (adagrasib) tablets for oral administration contain 200 mg of adagrasib. The following are inactive ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate (vegetable sourced), mannitol, and microcrystalline cellulose. The tablet film coating contains hypromellose, maltodextrin, medium chain triglycerides (vegetable sourced), polydextrose, talc,
and titanium dioxide. "
KRAZATI (adagrasib) Tablets: 200 mg.
Recommended dosage: 600 mg orally twice daily.
KRAZATI (adagrasib) is an inhibitor of the RAS GTPase family indicated for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), as determined by an FDA approved test, who have received at least one prior systemic therapy.